Sex difference and estrous cycle variations in amphetamine-elicited rotational behavior
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چکیده
منابع مشابه
Sex differences and estrous cycle variations in amphetamine-elicited rotational behavior.
The experiments reported here were designed to determine if there are sex- and/or estrus cycle-dependent differences in amphetamine (AMPH)-elicited rotational behavior in unlesioned rats. Whole brain or striatal levels of AMPH produced by systemic administration of the drug were also measured. At all doses tested (1.0-10.0 mg/kg) systemic administration of AMPH resulted in significantly higher ...
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The effects of gonadectomy on amphetamine-induced rotational behavior were studied in male and female rats. Different systemic doses were used to produce equivalent brain concentrations of the drug in each group, thereby controlling for sex differences in the metabolism of amphetamine. Ovariectomy of female rats significantly attenuated amphetamine-induced rotation, whereas castration of males ...
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ژورنال
عنوان ژورنال: European Journal of Pharmacology
سال: 1982
ISSN: 0014-2999
DOI: 10.1016/0014-2999(82)90178-9